Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
Users Online: 1541


Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Advertise Contacts Login 
Year : 2009  |  Volume : 50  |  Issue : 4  |  Page : 87-89

Gestational trophoblastic disease in a tertiary hospital in Nnewi, southeast Nigeria

Deparment of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, Nigeria

Correspondence Address:
S U Mbamara
PO box 354, Amaraku P. O. Imo State
Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and Permissions

Objective: This study was conducted to evaluate the prevalence of GTD and describe its clinical features and management in a tertiary level hospital inNnewi SoutheastNigeria. Methods: We studied retrospectively the cases of GTD that were proved histologically and managed in the department of Obstetrics and Gynaecology of Nnamdi Azikiwe University Teaching Hospital Nnewi over a 5 years period (200 - 2008). Results: The frequency of GTD inNnewi is 4.6 per 100 deliveries. Ten (66.7%) of the cases were choriocarcinoma while 5(33.3%) were hydatidiform mole. There was no case of invasive mole or placental site trophoblastic tumour (PSTT). The age range of the patients was 15 - 46 years with a mean of 31&@177; 8.6 years. There was no significant association between age and GTD (X2 = 4.5; p = 0.609) and between Parity and GTD (x2 =1.87; p = 0.171 ). Most of the patients (73.3%) presented in late second trimester and the comm onest mode of presentation was abnormal vaginal bleeding. The symphysio - fundal height was more than the estimated gestational age in 9(60%) of cases. All the patients made an earlier presentation in different peripheral hospitals and were managed as incomplete miscarriage prior to presentation in our hospital. The average duration of follow - up in these patients was 2.4 =3.2 weeks. Contraception use was documented in 3 (20%) of the patients. Conclusion: There was a high prevalence of GTD and notably choriocarcinoma. The associated mortality was high. There was lack of suspicion of the pathology among the primary healthcare providers. This study suggests that all cases of evacuation products should be subjected to histopathological examination. There is the need to emphasize the role of adequate and appropriate counselling in the management of the patients with GTD. Call and recall system should be introduced in the management of patients with GTD to improve their compliance to recommended management standard. This will improve the prognosis of the condition in our women.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded259    
    Comments [Add]    

Recommend this journal