Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
Users Online: 2188

 

Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Advertise Contacts Login 
     
ORIGINAL ARTICLE
Year : 2013  |  Volume : 54  |  Issue : 3  |  Page : 191-195

Acute renal failure in pregnancy: Tertiary centre experience from north Indian population


1 Department of Internal Medicine (Nephrology Unit), King George's Medical University, Lucknow, Uttar Pradesh, India
2 Department of Obstetrics and Gynaecology, King George's Medical University, Lucknow, Uttar Pradesh, India
3 Department of Critical Care, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
4 Department of Physiology, King George's Medical University, Lucknow, Uttar Pradesh, India

Correspondence Address:
Munna Lal Patel
Department of Internal Medicine (Nephrology Unit), King George's Medical University, Lucknow C-28, Sec-J, Aliganj, Near Sangam Chauraha, Lucknow, Uttar Pradesh - 226 024
India
Login to access the Email id

Source of Support: Research Cell, King George's Medical University, Lucknow (Grant no.: 4078/R. Cell-10 dated 07/01/2010), Conflict of Interest: None


DOI: 10.4103/0300-1652.114586

Rights and Permissions

Background: Obstetrical acute renal failure ARF is now a rare entity in the developed countries but still a common occurrence in developing countries. Delay in the diagnosis and late referral is associated with increased mortality. This study aimed to evaluate the contributing factors responsible for pregnancy-related acute kidney failure, its relation with mortality and morbidity and outcome measures in these patients. Materials and Methods: Total 520 patients of ARF of various aetiology were admitted, out of these 60 (11.5%) patients were pregnancy-related acute renal failure. Results: ARF Acute renal failure occurred in 32 (53.3%) cases in early part of their pregnancy, whereas in 28 (46.7%) cases in later of the pregnancy. Thirty-two (53.3%) patients had not received any antenatal visit, and had home delivery, 20 (33.4%) patients had delivered in hospitals but without antenatal care and eight (13.3%) patients received antenatal care and delivered in the hospitals. Anuria was observed in 23 (38.3%) cases, remaining 37 (61.7%) cases presented with oliguria. Septicemia was present in 25 (41.7%), hypertensive disorder of pregnancy in 20 (33.3%), haemorrhage in eight (13.3%), abortion in 5 (8.3%), haemolysis elevated liver enzymes low platelets counts (HELLP) syndrome in one (1.67%) and disseminated intravascular coagulation in one (1.67%). (61.7%) patients were not dialyzed, 33 (55%) recovered normal renal function with conservative treatment. Complete recovery was observed in 45 (75%) patients, five (8.4%) patients developed irreversible renal failure. Maternal mortality was nine (15%) and foetal loss was 25 (41.7%). Conclusion: Pregnancy-related ARF is usually a consequence of obstetric complications; it carries very high morbidity and mortality.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2658    
    Printed60    
    Emailed1    
    PDF Downloaded224    
    Comments [Add]    
    Cited by others 5    

Recommend this journal