Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
Users Online: 914

 

Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Advertise Contacts Login 
     
ORIGINAL ARTICLE
Year : 2015  |  Volume : 56  |  Issue : 1  |  Page : 39-42

Serum level of copper in patients with coronary artery disease


1 Department of Cardiology,Mazandaran University of Medical Sciences, Sari, Iran
2 Department of Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran
3 Department of Cardiac Surgery, Mazandaran University of Medical Sciences, Sari, Iran

Correspondence Address:
Vahid Mokhberi
Department of Cardiology,Mazandaran University of Medical Sciences, Sari
Iran
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0300-1652.149169

Rights and Permissions

Background: Atherosclerotic disease is the most important cause of mortality in the world. Oxidation is an important pathway in the pathogenesis of coronary artery disease (CAD) through oxidation of low-density lipoprotein (LDL) and free radical formation. Copper (Cu) is an essential micronutrient for enzymes that catalyse LDL oxidation reactions. Therefore, an evaluation of Cu in the atherosclerotic disease is important. Materials and Methods: In this study, 334 subjects without recent cardiac event and history of collagen vascular or infectious disease were investigated. All patients divided into four groups to evaluate severity of CAD according to Syntax scoring system. All groups were matched in cardiovascular risk factors. Results: The serum level of Cu was significantly higher in total atherosclerotic groups than normal group (P value = 0.001) and significantly increased with severity of atherosclerosis. Conclusion: The finding indicated that the serum level of Cu is higher in atherosclerotic patients and it increases with severity of atherosclerosis. Therefore, it may be possible that the basic relationship exist between serum Cu level and atherosclerosis and an association between Cu level and severity of atherosclerosis.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1892    
    Printed24    
    Emailed0    
    PDF Downloaded99    
    Comments [Add]    
    Cited by others 7    

Recommend this journal