Nigerian Medical Journal

: 2019  |  Volume : 60  |  Issue : 5  |  Page : 226--233

Medical treatment: An emerging standard in acute appendicitis?

Ikeoluwa Kendra Bolakale-Rufai, David O Irabor 
 Department of Surgery, University College Hospital, Ibadan, Oyo-State, Nigeria

Correspondence Address:
Ikeoluwa Kendra Bolakale-Rufai
Department of Surgery, University College Hospital, PMB 5116, Ibadan, Oyo-State

Appendicectomy has been accepted as the gold standard for the management of appendicitis over the years, but there has been an increasing evidence and trend toward the conservative approach to the management of appendicitis. The aim of this review is to search existing literature and to evaluate and compare the conservative and operative approaches to the management of appendicitis. An electronic search of published literature was conducted through Pubmed, Google Scholar, Embase, and Medline using a variety of search items to find relevant observational studies, randomized clinical trials, systematic reviews, and meta-analyses. Bibliographies of selected articles were also analyzed for publications of interest relevant to the scope of the topic. The articles that reported primary outcomes after the management of appendicitis, complications, economic implications, and duration of follow-up were reviewed in detail. The major primary outcomes show a high recurrence rate and failed treatment associated with the conservative management of appendicitis. The other outcomes obtained show that there is an increased incidence of complications associated with operative management. Economic implications and cost-effectiveness analysis show that conservative treatment may be preferred. The length of hospital stay was significantly higher in conservative approach to management; however, shorter time off activities was observed. In general, the conservative management of appendicitis is still regarded as safe, effective, and efficacious, and further research with well-constructed study design, and larger sample size is required.

How to cite this article:
Bolakale-Rufai IK, Irabor DO. Medical treatment: An emerging standard in acute appendicitis?.Niger Med J 2019;60:226-233

How to cite this URL:
Bolakale-Rufai IK, Irabor DO. Medical treatment: An emerging standard in acute appendicitis?. Niger Med J [serial online] 2019 [cited 2020 Apr 1 ];60:226-233
Available from:;year=2019;volume=60;issue=5;spage=226;epage=233;aulast=Bolakale-Rufai;type=0