| ORIGINAL ARTICLE |
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| Year : 2011 | Volume
: 52
| Issue : 2 | Page : 95-98 |
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Histologic analysis of incidental carcinomas of the prostate gland in portharcourt: A 10 year retrospective review
CC Obiorah, SO Nwosu
Anatomical Pathology Department, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria
Correspondence Address:
C C Obiorah
Department of Anatomical Pathology, University of Port Harcourt Teaching Hospital, Port Harcourt
Nigeria
 Source of Support: None, Conflict of Interest: None  | Check |
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Background: Incidental prostate cancers, i.e. cancers found in the specimens of men undergoing surgery for benign prostatic hyperplasia (BPH), have been regarded as non-lethal and harmless, therefore have most times , been left without treatment. However, recent studies have demonstrated otherwise, showing that there is significant mortality associated with the cancer. We determined the occurrence and evaluated the morphologic characteristics of incidental carcinomas of the prostate in a Teaching Hospital in Nigeria. Materials and methods: This was a retrospective review of prostatectomy specimens from patients clinically diagnosed of BPH between 1996 and 2005 at the University of Port Harcourt Teaching Hospital. Results: Age range of patients was 52-87 years, with mean of 67.4 years and peak age group of 60-69 years. Thirty-four (10.3%) of the reviewed 331 cases were positive for incidental carcinomas. All cases were adenocarcinomas. Twelve (35.3%) were well differentiated. Gleason score 5-6 constituted the majority of the cases 18 (52.9%). Eighteen cases (52.9%) were of large acinar morphologic pattern. Conclusion: The incidence of incidental carcinomas of the prostate in our environment is significant, consequently urologists should exercise high index of suspicion while attending to patients clinically diagnosed of BPH. The overall morphologic features portend fair prognosis and contrasts with the established late presenting, and advanced clinical carcinomas with poor prognosis. |
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