Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
Users Online: 40134

 

Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Advertise Contacts Login 
     
REVIEW ARTICLE
Year : 2014  |  Volume : 55  |  Issue : 2  |  Page : 93-98

Kidney injury, fluid, electrolyte and acid-base abnormalities in alcoholics


1 Department of Medicine, Kingsbrook Jewish Medical Center, Brooklyn, USA
2 Division of Nephrology, St. John's Episcopal Hospital, Southshore, New York, USA

Correspondence Address:
Onyekachi Ifudu
Division of Nephrology, St. John's Episcopal Hospital 327 Beach 19th Street Far Rockaway, New York 11691
USA
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0300-1652.129631

Rights and Permissions

In the 21 st century, alcoholism and the consequences of ethyl alcohol abuse are major public health concerns in the United States, affecting approximately 14 million people. Pertinent to the global impact of alcoholism is the World Health Organisation estimate that 140 million people worldwide suffer from alcohol dependence. Alcoholism and alcohol abuse are the third leading causes of preventable death in the United States. Alcohol dependence and alcohol abuse cost the United State an estimated US$220 billion in 2005, eclipsing the expense associated with cancer (US$196 billion) or obesity (US$133 billion). Orally ingested ethyl alcohol is absorbed rapidly without chemical change from the stomach and intestine, reaching maximum blood concentration in about an hour. Alcohol crosses capillary membranes by simple diffusion, affecting almost every organ system in the body by impacting a wide range of cellular functions. Alcohol causes metabolic derangements either directly, via its chemical by-product or secondarily through alcohol-induced disorders. Many of these alcohol-related metabolic disturbances are increased in severity by the malnutrition that is common in those with chronic alcoholism. This review focuses on the acute and chronic injurious consequences of alcohol ingestion on the kidney, as well as the fluid, electrolyte and acid-base abnormalities associated with acute and chronic ingestion of alcohol.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed7749    
    Printed220    
    Emailed0    
    PDF Downloaded365    
    Comments [Add]    
    Cited by others 19    

Recommend this journal